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Description
Alexa Fluor® 488 Rat Anti-Mouse CD184 Antibody (S-R670)Product Specification Host Rat Antigen CD184 Synonyms C X C chemokine receptor type 4; CXC R4; CXCR 4; Fusin; Leukocyte derived seven transmembrane domain receptor (LESTR); Pre B cell derived chemokine receptor (PB CKR); Stromal cell derived factor 1 receptor (SDF 1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4 Location Lysosome, Cell membrane, Cell junction Accession P70658 Clone Number S R670 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity
Product Specification
| Host | Rat |
| Antigen | CD184 |
| Synonyms | C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor (LESTR); Pre-B-cell-derived chemokine receptor (PB-CKR); Stromal cell-derived factor 1 receptor (SDF-1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4 |
| Location | Lysosome, Cell membrane, Cell junction |
| Accession | P70658 |
| Clone Number | S-R670 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse thymocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD184, also known as CXCR4, is a seven-transmembrane G-protein-coupled chemokine receptor that—after binding its unique ligand CXCL12 (SDF-1)—triggers multiple signaling cascades (PI3K/AKT, JAK/STAT, ERK1/2, Hedgehog) governing immune cell trafficking, plasma-cell homing to bone-marrow niches, embryonic development, hematopoiesis, angiogenesis, and cancer stem-cell maintenance, while its overexpression or mutations underlie WHIM syndrome, HIV entry, tumor progression and metastasis, making it a key therapeutic target in oncology and immunology.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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4.7 ★★★★★
Based on 28 reviews
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Product Reviews
★★★★★ 5
A nice sized wallet for front pocket keeping, holds the essentials & more quite well
Size: One Size, Color: Brown (Money Clip) 2
I like that I can keep cash, credit cards, ID and ATM cards all safely secured in this combo wallet/money clip that fits nicely in a back or front pants pocket (I keep mine in my front pocket). I've gotten this brand/style before, probably 6-8 years ago and it's the only wallet I'll use. I needed to replace mine as the spring metal clip does eventually wear through the leather at the rounded end of the money clip, but mine still functions just fine (I just wanted a new one for the holidays!) A well-made wallet and one I'll keep using and getting as long as I can find them.
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Reviewed in the United States on December 20, 2021
★★★★★ 5
Supple leather with a compact design.
Size: One Size, Color: Black II (Money Clip), Size: One Size, Color: Black II (Money Clip)
This is exactly what I was looking for and the price??? Unbelievably low. I saw a Carhartt one that I liked, but I didn’t care for the waxy look of leather on it so I looked on their website and they only offered it in that. I searched front pocket wallet on Amazon and I purchased this. It is a higher-quality leather, the price tag inside says $55. I paid under $18. The one thing I did like about the Carhartt one, it had a magnetic strap for the cash where as this one has a fixed money clip, but I see no problems with the design. Very minimalist design.
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Reviewed in the United States on August 16, 2025
★★★★★ 5
Timberline pocket Wallet
Size: One Size, Color: Brown (Money Clip) 2
good deal excellent product
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Reviewed in the United States on July 22, 2025
★★★★★ 5
Second Best Bifold I’ve Owned
Color: Black
I’ve gone through a lot of wallets over the years (cheap ones, expensive ones, slim cardholders, you name it), and this Timberland bifold with the attached flip pocket is easily the best all-around wallet I’ve ever carried.
The leather is excellent: full-grain, soft right out of the box, and it’s aged beautifully in just a few months with a rich patina that actually looks better with every scratch and scuff. Build quality is top-notch: tight, even stitching, no loose threads, and the edges are finished cleanly. Four months of daily front-pocket carry and it still looks practically new.
Layout is perfect for me. Six card slots plus the two slip pockets behind them handle everything I need (10 cards + a few folded bills) without getting bulky. The attached flip ID window is a game-changer; I keep my driver’s license and work badge there and can show either in seconds without opening the wallet. Cash fits easily in the full-length bill compartment.
It’s genuinely slim for a traditional leather bifold, sits comfortably in both front and back pockets, and never feels like a brick. The embossed Timberland logo is subtle and classy.
At this point I can’t imagine switching to anything else. It’s durable, functional, looks sharp, and was a fraction of the price of some “luxury” wallets that didn’t last half as long. If you want a classic leather bifold that actually delivers, this is it. 100% recommended; already planning to buy another as a backup.
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Reviewed in the United States on December 6, 2025
★★★★★ 5
Rugged Timberland Quality—The Best Bifold for "Double ID" Needs
Color: Black (Sportz)
Design & Capacity:
I’ve been using this wallet for two weeks, and it’s a powerhouse for organization. The attached flip pocket is a game-changer for me because I have to carry both a driver's license and a work security badge. The two ID windows let me show both without digging through card slots.
Genuine Leather: Looks and smells premium; will likely weather nicely with age.
The Slimness Factor:
Timberland calls this a "slimfold," and while it is thinner than a traditional trifold, the flip-out pocket does add some depth. With 6 cards and 5 bills, it measures about 0.75 inches thick. It fits comfortably in my back pocket, but it might be a bit much for a front-pocket-only user.
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Reviewed in the United States on February 5, 2026